Karyotypic Analysis of Acute Myeloid Leukemia (AML) in 75 Referral Cases: One Year Report

Ketan K VAGHASIA; Vidhi M BHATT; Parth S SHAH; Nidhi D SHAH; Mandava V RAO; Sandip C SHAH

Vol 2 No 4 (2016) / 166-168 Research articles

Karyotypic Analysis of Acute Myeloid Leukemia (AML) in 75 Referral Cases: One Year Report

Ketan K VAGHASIA

Vidhi M BHATT

Parth S SHAH

Nidhi D SHAH

Mandava V RAO

Sandip C SHAH

More author's info

Ketan K VAGHASIA
Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat

Vidhi M BHATT
Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat

Parth S SHAH
Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat

Nidhi D SHAH
Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat

Mandava V RAO
Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat; School of Sciences, Gujarat University, Ahmedabad, Gujarat

pvphuc@bmrat.org

Sandip C SHAH
Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat

Submitted: Sep 22, 2021 | Published: Dec 31, 2016

Vol 2 No 4 (2016) | | Page No.: 166-168

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K VAGHASIA, K., M BHATT, V., S SHAH, P., D SHAH, N., V RAO, M., & C SHAH, S. (2016). Karyotypic Analysis of Acute Myeloid Leukemia (AML) in 75 Referral Cases: One Year Report. Biotechnological Research, 2(4), 166-168. Retrieved from http://br.biomedpress.org/index.php/br/article/view/729

Copyrights: Ketan K VAGHASIA, Vidhi M BHATT, Parth S SHAH, Nidhi D SHAH, Mandava V RAO, Sandip C SHAH, 2016. License:

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

We have analyzed 75 referral cases of Acute Myeloid Leukemia (AML) registered in our Research Institute, Supratech Genopath Laboratory of Ahmedabad. Karyotype analysis of bone marrow and blood samples revealed 7 cases (9.3%) were AML positive. Out of these cases, 3 patients (4%) have recurrent chromosomal anomalies of t(8;21) and t(15;17) and other 4 (5.3%) had AML with MDS related changes in which one karyotype had 4 chromosomal abnormalities viz, two each of trisomy and monosomy respectively . This group has poor prognosis.