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Karyotypic Analysis of Acute Myeloid Leukemia (AML) in 75 Referral Cases: One Year Report

Ketan K VAGHASIA 1
Vidhi M BHATT 1
Parth S SHAH 1
Nidhi D SHAH 1
Mandava V RAO 1, 2, *
Sandip C SHAH 1

  1. Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat
  2. School of Sciences, Gujarat University, Ahmedabad, Gujarat
Correspondence to: Mandava V RAO, Supratech Genopath Laboratory and Research Institute, Ahmedabad, Gujarat; School of Sciences, Gujarat University, Ahmedabad, Gujarat. Email: pvphuc@bmrat.org.
Volume & Issue: Vol. 2 No. 4 (2016) | Page No.: 166-168 |
Published: 2016-12-31

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Copyright © 2016 by the author(s).

Copyright The Author(s) 2017. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

We have analyzed 75 referral cases of Acute Myeloid Leukemia (AML) registered in our Research Institute, Supratech Genopath Laboratory of Ahmedabad. Karyotype analysis of bone marrow and blood samples revealed 7 cases (9.3%) were AML positive. Out of these cases, 3 patients (4%) have recurrent chromosomal anomalies of t(8;21) and t(15;17) and other 4 (5.3%) had AML with MDS related changes in which one karyotype had 4 chromosomal abnormalities viz, two each of trisomy and monosomy respectively . This group has poor prognosis.

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