Abstract

The use of herbal plants and their extracts have been utilized by all over the world for its various biological activities. The use of ethanolic Pithecellobium dulce extract has been analyzed for its anti-inflammatory and antibacterial activities. For this, Streptococcus pyrogenes, Staphylococcus aureus, Escherichia coli and Klebsiella pneumonia have been studied against the P. dulce extract. The result which shows the presence of many difference secondary metabolites such as alkaloids, flavonoids, glycosides, phenols, steroids, tannins, terpenoids and saponins have been detected. The anti-inflammatory responses such as percentage of inhibition of protein denaturation and HRBC membrane stabilization has showed an increase response when compared with the standard drug Aspirin of about 62.80 and 59.25% respectively. Also the antibacterial response showed a positive response when compared with the standard drug gentamycin at the lower concentration. Hence, the ethanolic extract of P. dulce can be used as a potential agent as antiinflammatory and anti-bacterial compounds.